A Study of the Bacteria Found in Cancerous and Non-cancerous Breast Tissue


About this study

The purpose of this study is to see if having different kinds of bacteria genes in breast tissue may be connected to the risk of getting breast cancer. 

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Patients age 18 years and greater and able to give informed consent.
  • Planned breast procedure other than mastectomy. 
  • Malignant or benign disease as operative indication.

Exclusion Criteria:

  • Antibiotic use within 14 days of operation .
  • Steroid use within 14 days of operation (other than topical or inhaled steroids).
  • Proton pump inhibitor medications including pantoprazole and omeprazole within 14 days of operation .
  • Operation performed for clinical infection  .
  • Planned mastectomy.
  • Prior history of breast cancer or any other invasive cancer other than non-melanoma skin cancer .
  • Documented chlorhexidine gluconate allergy.
  • Male patients.
  • Organ transplant and bone marrow transplant patients. 
  • Vulnerable subjects (prisoners, institutionalized individuals).
  • Non-English speakers without adequate interpreter assistance.
  • Breast operation other than percutaneous needle biopsy within previous 3 months.


Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Tina Hieken, M.D.

Open for enrollment

Contact information:

Marcia Mahlman CCRP



More information


Publications are currently not available

Additional contact information

Cancer-related trials contact form

Phone: 855-776-0015 (toll-free)

International patient clinical studies questions