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Healthy Volunteer

What is this?
A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

What is this?
During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 38 for

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  1. Transcatheter Aortic Valve Replacement to UNload the Left Ventricle in Patients With ADvanced Heart Failure (TAVR UNLOAD)

    Rochester, MN

  2. Cara CDRM (Conduction Disturbance Risk Monitor) 2.0

    Rochester, MN

  3. An Evolut™ EXPAND TAVR II Pivotal Trial

    Rochester, MN

  4. PROACT Xa - A Trial to Determine if Participants With an On-X Aortic Valve Can be Maintained Safely on Apixaban

    Rochester, MN

  5. PARADIGM: Amplatzer Valvular Plug for PVL Closure

    Rochester, MN

  6. Left Ventricular Ejection Hemodynamics in Patients with Hypertrophic Cardiomyopathy and Valvular Aortic Stenosis

    Rochester, MN

  7. Behavior of Valve Leaflets

    Rochester, MN

  8. SMall Annuli Randomized To Evolut™ or SAPIEN™ Trial

    Rochester, MN

  9. Cardiac Vascular Reconstruction DynaCT for TAVI Procedures

    Rochester, MN

  10. Transfemoral Replacement of Aortic Valve With HLT MeriDIAN Valve Early Feasibility Trial

    Rochester, MN

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