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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 30 for Migraine

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  1. Digital Biomarkers for Objectively and Remotely Monitoring Migraine

    Scottsdale/Phoenix, AZ

  2. Understanding Post-Traumatic Headache: Forward Translation of a Posttraumatic Headache Animal Model to Posttraumatic Headache in the Human

    Scottsdale/Phoenix, AZ

  3. Efficacy, Safety, and Tolerability of Oral Ubrogepant in the Acute Treatment of Migraine

    Scottsdale/Phoenix, AZ

  4. Occipital Nerve Stimulation (ONS) for Migraine: OPTIMISE

    Scottsdale/Phoenix, AZ

  5. Verapamil vs. Sertraline for Vestibular Migraine & Chronic Subjective Dizziness

    Scottsdale/Phoenix, AZ, Rochester, MN

  6. The Childhood and Adolescent Migraine Prevention Study

    Rochester, MN

  7. A Multicenter Assessment of ALD403 in Chronic Migraine

    Scottsdale/Phoenix, AZ

  8. The MOTS (Medication Overuse Treatment Strategy) Trial

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  9. A Study to Compare the Effectiveness of Using Tints or Thin-Films on Eye Glass Lens to Reduce Light Sensitivity for Patients with Chronic Migraine

    Scottsdale/Phoenix, AZ

  10. A Study of Non-invasive Vagus Nerve Stimulation for the Prevention of Migraines

    Scottsdale/Phoenix, AZ

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