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Healthy Volunteer

What is this?
A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

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  1. A Study to Evaluate the Accuracy of the Length-109 Probe Set Panel (a Genetic Test) in Predicting Response to Golimumab in Participants with Moderately to Severely Active Ulcerative Colitis

    Rochester, MN

  2. rTMS for Depressed Teens: A Sham-Controlled Trial, Part 2

    Rochester, MN

  3. Occipital Nerve Stimulation (ONS) for Migraine: OPTIMISE

    Scottsdale/Phoenix, AZ

  4. Muscle Protein Metabolism in Obesity

    Scottsdale/Phoenix, AZ

  5. Effectiveness of Deep Brain Stimulation for Treating People with Treatment Resistant Obsessive-Compulsive Disorder

  6. Phase 3, Randomized, Placebo-Controlled, Double-Blinded Trial of the Combined Lysis of Thrombus with Ultrasound and Systemic Tissue Plasminogen Activator (tPA) for Emergent Revascularization in Acute Ischemic Stroke

    Scottsdale/Phoenix, AZ

  7. Simtuzumab (GS-6624) in the Treatment of Cirrhosis Due to NASH

    Scottsdale/Phoenix, AZ

  8. Pilot Project on External Vestibular Prosthesis in Chronic Subjective Dizziness

    Rochester, MN

  9. Does Tranexamic Acid Reduce the Need for Blood Transfusions in Patients Undergoing Hip Fracture Surgery?

    Rochester, MN

  10. Cough Reflex Sensitivity and Bronchial Hyper-responsiveness

    Jacksonville, FL

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