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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

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  1. A Study to Compare Letrozole With or Without Paclitaxel and Carboplatin in Treating Patients With Stage II-IV Ovarian or Primary Peritoneal Cancer

    Albert Lea, MN, Rochester, MN

  2. A Study Testing the Effectiveness and Safety of KPL-301 in Patients with Giant Cell Arteritis

    Rochester, MN

  3. Study of Pembrolizumab Combined with Decitabine and Pralatrexate in Peripheral T-cell Lymphoma and Cutaneous T-cell Lymphoma

    Rochester, MN

  4. A Study to Evaluate Durvalumab Alone or in Combination With Novel Agents in Subjects With NSCLC

  5. Veliparib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Malignant Glioma Without H3 K27M or BRAFV600 Mutations

    Rochester, MN

  6. Estradiol in Treating Patients With ER Beta Positive, Triple Negative Locally Advanced or Metastatic Breast Cancer

    Rochester, MN, Jacksonville, FL

  7. A Study of Automated Myocardial Performance Index Before, During and After Fetal Surgeries using Samsung HERA W10

    Rochester, MN

  8. A Study to Evaluate Decision-support Interventions for Atrial Fibrillation (RED-AF)

    Rochester, MN

  9. A Study to Evaluate the Feasibility of Daily, Long-Term, Intermittent Fasting for Men on PSA Surveillance Following Radical Prostatectomy

    Rochester, MN

  10. Cixutumumab in Treating Patients With Relapsed or Refractory Solid Tumors

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