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Oral Ketamine in the Treatment of Depression and Anxiety in Patients with Cancer

Scottsdale/Phoenix, AZ
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Oral Ketamine in the Treatment of Depression and Anxiety in Patients with Cancer
- Study type:
  Interventional
  Describes the nature of a clinical study. Types include:
  
  Observational study — observes people and measures outcomes without affecting results.
  
  Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
  
  Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
- Study phase:
  2
  During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.
About this study

Depression is common in patients with cancer. Current medications for depression, while effective, take several weeks to take effect. Ketamine has emerged as a drug with promise for cancer patients. In two reported cases, a single dose of ketamine induced rapid and moderately sustained symptom reduction in depression and anxiety with no adverse side effects. Benefit was seen in as little as 1 hour and sustained up to 30 days. This study is a randomized, double-blind, placebo-controlled investigation testing whether a single dose of ketamine improves depression and anxiety relative to placebo in patients with cancer.

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status Contact

Scottsdale/Phoenix, Ariz.

Closed for enrollment
View complete study & contact information

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Site IRB:
Scottsdale/Phoenix, Arizona: 12-001156

NCT ID:
NCT01680172

Sponsor Protocol Number:
12-001156
A Study of Mechanisms of Altered Ventilatory Control in Heart Failure

Rochester, MN
- See Details
A Study of Mechanisms of Altered Ventilatory Control in Heart Failure
- Study type:
  Interventional
  Describes the nature of a clinical study. Types include:
  
  Observational study — observes people and measures outcomes without affecting results.
  
  Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
  
  Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
About this study

This study is being done because the investigators are trying to understand how feedback from the muscles can influence your blood pressure and breathing during exercise, and if the investigators can reduce this response in heart failure patients. The investigators are also trying to determine ways to improve tolerance to exercise in heart failure patients.

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status Contact

Rochester, Minn.

Closed for enrollment
View complete study & contact information

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Site IRB:
Rochester, Minnesota: 12-005318

NCT ID:
NCT02421341

Sponsor Protocol Number:
12-005318

Mayo Clinic Location	Status	Contact
Scottsdale/Phoenix, Ariz.	Closed for enrollment	View complete study & contact information

Mayo Clinic Location	Status	Contact
Rochester, Minn.	Closed for enrollment	View complete study & contact information

Golden Calf Trial

La Crosse, WI, Eau Claire, WI, Rochester, MN

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Golden Calf Trial

Study type:
Interventional
Describes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.

About this study

The purpose of this study is to determine whether prescribing apixaban (Eliquis®) is more effective in treating and preventing pulmonary embolisms and subsequent DVTs than monitoring the calf DVT with ultrasound imaging alone.

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location	Status	Contact
La Crosse, Wis.	Closed for enrollment	View complete study & contact information
Eau Claire, Wis.	Closed for enrollment
Rochester, Minn.	Closed for enrollment

Print study details

Site IRB:
- La Crosse, Wisconsin: 17-009022
- Eau Claire, Wisconsin: 17-009022
- Rochester, Minnesota: 17-009022
NCT ID:
NCT03590743
Sponsor Protocol Number:
17-009022

Mayo Clinic Location	Status	Contact
Rochester, Minn.	Closed for enrollment	View complete study & contact information

Mayo Clinic Location	Status	Contact
Rochester, Minn.	Closed for enrollment	View complete study & contact information

Mayo Clinic Location	Status	Contact
Rochester, Minn.	Closed for enrollment	View complete study & contact information

Mayo Clinic Location	Status	Contact
Rochester, Minn.	Closed for enrollment	View complete study & contact information

A Study of the Use of Smartphone Videos to Aid in Evaluation of Epileptic Seizures

Jacksonville, FL, Scottsdale/Phoenix, AZ, Rochester, MN

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A Study of the Use of Smartphone Videos to Aid in Evaluation of Epileptic Seizures

Study type:
Interventional
Describes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.

About this study

The purpose of this study is to find out if home-recorded Smartphone videos can be used to accurately diagnose epilepsy in patients seeking evaluation for seizures. The idea is to compare the home-recorded video to video-EEG monitoring, which is the current gold-standard for diagnosis.

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location	Status	Contact
Jacksonville, Fla.	Closed for enrollment	View complete study & contact information
Scottsdale/Phoenix, Ariz.	Closed for enrollment
Rochester, Minn.	Closed for enrollment

Print study details

Site IRB:
- Jacksonville, Florida: 13-004486
- Scottsdale/Phoenix, Arizona: 13-004486
- Rochester, Minnesota: 13-004486
Sponsor Protocol Number:
13-004486

Brentuximab Vedotin and Combination Chemotherapy in Treating Younger Patients with Newly Diagnosed Hodgkin Lymphoma

Rochester, MN
- See Details
Brentuximab Vedotin and Combination Chemotherapy in Treating Younger Patients with Newly Diagnosed Hodgkin Lymphoma
- Study phase:
  3
  During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.
Print study details
NCT ID:
NCT02166463
Study to Assess the Decline in Cognitive Function Using Standardized Neurocognitive Assessment in Atrial Fibrillation Patients Treated with Apixaban Versus Warfarin

Rochester, MN
- See Details
Study to Assess the Decline in Cognitive Function Using Standardized Neurocognitive Assessment in Atrial Fibrillation Patients Treated with Apixaban Versus Warfarin
- Study type:
  Interventional
  Describes the nature of a clinical study. Types include:
  
  Observational study — observes people and measures outcomes without affecting results.
  
  Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
  
  Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
- Study phase:
  3
  During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.
About this study

The purpose of this study is to assess the decline in cognitive function using standardized neurocognitive assessment in Atrial Fibrilation patients treated with Apixaban vs Warfarin.

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status Contact

Rochester, Minn.

Closed for enrollment
View complete study & contact information

Print study details
Site IRB:
Rochester, Minnesota: 17-010544

NCT ID:
NCT03839355

Sponsor Protocol Number:
17-010544

Mayo Clinic Location	Status	Contact
Rochester, Minn.	Closed for enrollment	View complete study & contact information

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Search Results 621-630 of 11566

Oral Ketamine in the Treatment of Depression and Anxiety in Patients with Cancer

A Study of Mechanisms of Altered Ventilatory Control in Heart Failure

Golden Calf Trial

A Study to Compare the Outcome of Primary Anatomic Shoulder Arthroplasty Using the Stryker ReUnion System with Implantation of Either a Peg or Keel Glenoid Construction.

Mayo Clinic Pilot Studies towards Optimizing Quality of Life and Outcomes in VAD Patients

A Study to to Determine the Impact of a Mobile Health Application on Rheumatoid Arthritis Shared Decision Making

A Study of Pharmacogenomics (PGx) Results and Clinical Data of Chronic Pain Patients to Assess Current and Future Therapeutic Relevance

A Study of the Use of Smartphone Videos to Aid in Evaluation of Epileptic Seizures

Brentuximab Vedotin and Combination Chemotherapy in Treating Younger Patients with Newly Diagnosed Hodgkin Lymphoma

Study to Assess the Decline in Cognitive Function Using Standardized Neurocognitive Assessment in Atrial Fibrillation Patients Treated with Apixaban Versus Warfarin

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