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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 6151-6160 of 10871

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  1. A Study of the Effect of Lack of Sleep on Blood Pressure

    Rochester, MN

  2. Evaluation of Dual Therapy with Dabigatran versus Triple Therapy with Warfarin in Patients with Atrial Fibrillation that Undergo a Percutaneous Coronary Intervention with Stenting (REDUAL-PCI)

    Scottsdale/Phoenix, AZ

  3. A Study Using Chemotherapy Followed by Radiation Therapy in Treating Younger Patients with Newly Diagnosed Localized Central Nervous System Germ Cell Tumors

    Rochester, MN

  4. A Study of Using Caspofungin Acetate, Fluconazole, or Voriconazole in Preventing Fungal Infections in Patients Following Donor Stem Cell Transplant

    Rochester, MN

  5. Evaluate how Measurements of the Cornea Correlate to the Function of the Inside Lining (Endothelium) of the Cornea

  6. A Study to Develop Processes for Tissue Growth for Use in Reconstruction Surgeries

    Scottsdale/Phoenix, AZ

  7. Perfusion Assessment of Wound Closure Techniques in Primary Total Knee Arthroplasty

    Rochester, MN

  8. Neurotransmitter Measurements Using Wireless Instantaneous Neurotransmitter Concentration System (WINCS) During Deep Brain Stimulation Neurosurgery

    Rochester, MN

  9. Evaluate Risk/Benefit of Nab Paclitaxel in Combination With Gemcitabine and Carboplatin Compared to Gemcitabine and Carboplatin in Triple Negative Metastatic Breast Cancer (or Metastatic Triple Negative Breast Cancer)

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  10. Use of Cardiac Magnetic Resonance Imaging (cMRI) and Echocardiogram to Diagnose Constrictive Pericarditis and Restrictive Cardiomyopathy

    Rochester, MN

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