A Study Of Dry Needling With Electrical Stimulation In Restless Legs Syndrome

Overview

About this study

The purpose of this study is to examine the effects of dry needling with electrical stimulation (DNES) on sleep quality, symptom severity, and function in individuals with restless legs syndrome.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

​​​​​​Inclusion Criteria:

  • Age 18 - 75 years 

  • Clinical diagnosis of restless legs syndrome

     

Exclusion Criteria: 

  • Active cancer diagnoses

  • Neuropathic pain (e.g., lumbosacral radiculopathy and/or diabetic neuropathy),

  • Pregnancy

  • Immunocompromised disease (e.g., HIV, AIDS, lupus)

  • Insufficient English-language skills to complete all questionnaires

  • Inability to maintain treatment positions

  • Contraindications to dry needling:

    • Presence of needle phobia

    • History of abnormal reaction to needling or injection

    • History of bleeding disorder

Note: Other protocol defined Inclusion/Exclusion criteria may apply.

Eligibility last updated 4/06/2026. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Ray Lunasin, Ph.D., P.T., D.P.T.

Contact us for the latest status

Contact information:

Ray Lunasin

5075380839

lunasin.ray@mayo.edu

More information

Publications

Publications are currently not available