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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 6161-6170 of 10871

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  1. Cryo Balloon for Residual Barrett's Esophagus

  2. Microbiota Restoration Therapy for Recurrent Clostridium Difficile Infection

    Rochester, MN

  3. LGX818 and MEK162 in Combination With a Third Agent (BKM120, LEE011, BGJ398 or INC280) in Advanced BRAF Melanoma

  4. Presatovir in Hematopoietic Cell Transplant Recipients With Respiratory Syncytial Virus (RSV) Infection of the Lower Respiratory Tract

    Scottsdale/Phoenix, AZ

  5. Pentoxifylline Treatment in Acute Pancreatitis (AP)

    Rochester, MN

  6. Expanded Access Program With Nivolumab (BMS-936558) in Combination With Ipilimumab (Yervoy®) in Anti-CTLA-4 Treatment-Naïve Subjects With Unresectable or Metastatic Melanoma (CheckMate 218)

  7. A Clinical Trial to Evaluate the HeartWare Ventricular Assist System (ENDURANCE SUPPLEMENTAL TRIAL)

    Rochester, MN

  8. A Study of Statins for Acutely Injured Lungs from Sepsis

    Jacksonville, FL, Rochester, MN

  9. A Study to Compare Docetaxel/Prednisone to Docetaxel/Prednisone Combined with OGX-011 in Men with Prostate Cancer

    Rochester, MN

  10. A Study of the Effect of Ileal Bile Acid Transporter Inhibitor for Functional Constipation

    Rochester, MN

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