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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 5931-5940 of 11739

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  1. MRI Study To Identify Functional and Structural Changes That Correlate with Patient Improvement When Imaging the Brain Pre-and-Post Erenumab

    Scottsdale/Phoenix, AZ

  2. A Study of Measuring Oculomotor and Cognitive Performance During Cerebral Hypoxia Using the Oculo-Cognitive Addition Test (OCAT)

    Scottsdale/Phoenix, AZ

  3. A Study Of CTD402 In T-ALL/LBL Patients

    Rochester, MN

  4. Study Of Datopotamab Deruxtecan (Dato-DXd) In Combination With Durvalumab And Carboplatin For First-Line Treatment Of Patients With Advanced NSCLC Without Actionable Genomic Alterations

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  5. Lidocaine and Conducted Dilation in Humans

    Rochester, MN

  6. Automatic Periodic Stimulation and Continuous Electromyography (EMG) for Facial Nerve Monitoring During Parotidectomy

    Rochester, MN

  7. Everolimus and Alemtuzumab in Treating Patients With Recurrent Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

  8. Aurora A Kinase Inhibitor MLN8237 and Bortezomib in Treating Patients With Relapsed or Refractory Multiple Myeloma

    Scottsdale/Phoenix, AZ, Rochester, MN

  9. Activity Monitoring in Patients Undergoing Pain Rehabilitation

    Jacksonville, FL, Rochester, MN

  10. Mechanistic Effects of Health Coaching to Reduce COPD Hospitalizations

    Rochester, MN, Scottsdale/Phoenix, AZ

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