Lidocaine and Conducted Dilation in Humans


About this study

To determine if lidocaine administered in the brachial arteries of volunteers alters the vasodilator responses to a brief forearm contraction and bolus infusions of the vasodilators acetylcholine and nitroprusside. 

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Healthy male and female (n=10) participants between 18-40 years old will be recruited for this study.

Participants must be non-smokers, have no current cardiac, renal, vascular, pulmonary, endocrine, or neurological disease.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Michael Joyner, M.D.

Closed for enrollment

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