Lidocaine and Conducted Dilation in Humans


  • Study type

  • Study IDs

  • Describes the nature of a clinical study. Types include:

    • Observational study — observes people and measures outcomes without affecting results.
    • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
    • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
  • Site IRB
    • Rochester, Minnesota: 16-010109
    Sponsor Protocol Number: 16-010109

About this study

To determine if lidocaine administered in the brachial arteries of volunteers alters the vasodilator responses to a brief forearm contraction and bolus infusions of the vasodilators acetylcholine and nitroprusside. 

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

See eligibility criteria

Healthy male and female (n=10) participants between 18-40 years old will be recruited for this study.

Participants must be non-smokers, have no current cardiac, renal, vascular, pulmonary, endocrine, or neurological disease.

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Michael Joyner, M.D.

Closed for enrollment

Contact information:

Shelly Roberts R.N.