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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 5921-5930 of 11715

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  1. Mucosal Impedance and Eosinophilic Esophagitis

    Rochester, MN

  2. Evaluating the Effectiveness of Intravenous Immunoglobulin Therapy in Autoimmune Autonomic Ganglionopathy

    Rochester, MN

  3. MRI Study To Identify Functional and Structural Changes That Correlate with Patient Improvement When Imaging the Brain Pre-and-Post Erenumab

    Scottsdale/Phoenix, AZ

  4. A Study of Measuring Oculomotor and Cognitive Performance During Cerebral Hypoxia Using the Oculo-Cognitive Addition Test (OCAT)

    Scottsdale/Phoenix, AZ

  5. Lidocaine and Conducted Dilation in Humans

    Rochester, MN

  6. Automatic Periodic Stimulation and Continuous Electromyography (EMG) for Facial Nerve Monitoring During Parotidectomy

    Rochester, MN

  7. Everolimus and Alemtuzumab in Treating Patients With Recurrent Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

  8. Aurora A Kinase Inhibitor MLN8237 and Bortezomib in Treating Patients With Relapsed or Refractory Multiple Myeloma

    Scottsdale/Phoenix, AZ, Rochester, MN

  9. Clinical Evaluation of the CADence Device in Detection of Coronary Artery Diseases

    Rochester, MN

  10. The Relationship between Star Excursion Balance Test Performance and Hip Strength, Self- Report Outcomes and Core Stability in Patients 12 Weeks Status Post Hip Arthroscopy

    Minneapolis, MN

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