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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 31-40 of 55 for

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  1. Study Of The Bria-IMT Regimen And CPI Vs Physicians' Choice In Advanced Metastatic Breast Cancer. (BRIA-ABC)

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  2. A Feasibility Study To Evaluate The Safety Of The TheraSphere Glioblastoma (GBM) Device In Patients With Recurrent GBM

    Jacksonville, FL

  3. A Study to Compare Optimal MRI Timing for Pre-surgical Planning to LINAC-based Therapy

    Rochester, MN

  4. Pediatric Extracranial Solid Tumor Biorepository

    Rochester, MN

  5. Neuro-Oncology Care Priorities of Patients and Caregivers

    Rochester, MN

  6. Brain Tumor-Gut Axis Human Biorepository

    Jacksonville, FL

  7. A Study to Evaluate Advanced Development of Desorption Electrospray Ionization Mass Spectrometry for Intraoperative Molecular Diagnosis of Brain Cancer

    Jacksonville, FL

  8. Human Blood and Tissues Repository for Neuroscience Research

    Jacksonville, FL

  9. A Study to Explore if it is Possible to Successfully Obtain Optical Coherence Tomography (OCT) Imaging and Data While Patients Undergo Brain Surgery

    Jacksonville, FL

  10. Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies

    Rochester, MN

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