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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

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  1. MC230813 A Study Of Golcadomide With Rituximab Prior To CAR-T With Relapsed Or Primary Refractory Aggressive B-cell Non-Hodgkin Lymphoma (NHL)

    Albert Lea, MN, Scottsdale/Phoenix, AZ, Eau Claire, WI, Jacksonville, FL, La Crosse, WI, Mankato, MN, Rochester, MN

  2. Study Of Trastuzumab Deruxtecan, Pembrolizumab, And Platinum-based Chemotherapy In First-line HER2 Overexpressing Non-small Cell Lung Cancer

    Rochester, MN

  3. Study Of Natriuretic Peptide Receptor 1 (NPR1) Antagonist In Adult Patients With Postural Orthostatic Tachycardia Syndrome (POTS)

    Rochester, MN

  4. Myoelectric SoftHand Pro to Improve Prosthetic Function for People With Below-elbow Amputations: A Feasibility Study

    Rochester, MN

  5. Combination Chemotherapy in Treating Young Patients With Newly Diagnosed High-Risk B Acute Lymphoblastic Leukemia and Ph-Like TKI Sensitive Mutations

    Rochester, MN

  6. Low-Dose or High-Dose Lenalidomide in Treating Children with Recurrent, Refractory, or Progressive Pilocytic Astrocytoma or Optic Pathway Glioma

    Rochester, MN

  7. Transforming Non-Invasive Liver Disease Detection by Magnetic Resonance Elastography

    Rochester, MN

  8. A Study of Macitentan in Pulmonary Hypertension After Left Ventricular Assist Device Implantation

    Scottsdale/Phoenix, AZ

  9. A Study to Evaluate Utilizing MRI for Earlier Diagnosis of Rheumatoid Arthritis

    Rochester, MN

  10. Extended Access of Momelotinib in Adults With Myelofibrosis

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

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