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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1481-1490 of 10980

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  1. Early Feasibility Study of the Edwards FORMA Tricuspid Transcatheter Repair System

    Rochester, MN

  2. Using a Small Wearable Device to Track Orientation and Activity in Pregnant Patients

    Rochester, MN

  3. Effect of TAK-954 on Gastrointestinal and Colonic Transit in Diabetic or Idiopathic Gastroparesis Participants

    Rochester, MN

  4. OTL38 for Intraoperative Imaging of Folate Receptor Positive Lung Nodules

  5. Phase II Study of NGC-Triple Regimen in Potentially Resectable Pancreatic Cancer Patients

    Scottsdale/Phoenix, AZ, Rochester, MN

  6. Safety and Effectiveness of Esophageal Self Dilation for Benign Refractory Esophageal Stricture Management

    Scottsdale/Phoenix, AZ, Rochester, MN

  7. Testing an Active Form of Tamoxifen (4-hydroxytamoxifen) Delivered Through the Breast Skin to Control Ductal Carcinoma in Situ (DCIS) of the Breast

  8. Efficacy of Two Doses of Duloxetine & Amitriptyline in Interstitial Lung Disease-related Cough (MACS-2)

    Rochester, MN

  9. A Study to Evaluate the Effect of Metformin on Frailty in 12 Subjects (6 Metformin/6 Placebo in a Randomized Fashion)

    Rochester, MN

  10. A Study of Cemiplimab in Patients With Advanced Basal Cell Carcinoma Who Experienced Progression of Disease on Hedgehog Pathway Inhibitor Therapy, or Were Intolerant of Prior Hedgehog Pathway Inhibitor Therapy

    Scottsdale/Phoenix, AZ

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