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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 74 for vascular surgery

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  1. ELUVIA™ Drug-eluting Stent Versus Zilver® PTX® Stent

    Rochester, MN

  2. Clinical Study of the Treovance Stent-Graft for Patients With Abdominal Aortic Aneurysms

    Rochester, MN

  3. Cardiac Vascular Reconstruction DynaCT for TAVI Procedures

    Rochester, MN

  4. Evaluating Transcutaneous Electrical Nerve Stimulation for Postoperative Pain After Video-Assisted Thoracotomy Surgery

    Rochester, MN

  5. Assessment of the Embolization of Neurovascular Lesions Using the Penumbra Smart Coil

    Jacksonville, FL

  6. A Study to Compare Radiation Exposures between Two Standard-of-care Methods of Abdominal Aortic Aneurysm Repair

    Scottsdale/Phoenix, AZ

  7. Best Endovascular vs. Best Surgical Therapy in Patients With Critical Limb Ischemia

    Rochester, MN

  8. Ultrasonic Energy for Pulmonary Artery Branch Sealing During VATS Lobectomy

    Rochester, MN

  9. A Study to Assess Outcomes of Patients Treated with AFX System Compared to Other EVAR Devices

    Jacksonville, FL

  10. Treatment for CI-DME in Eyes With Very Good VA Study

    Rochester, MN

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