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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 31-40 of 81 for vascular surgery

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  1. Lp-PLA2, Progenitor Cells and Coronary Atherosclerosis in Humans AIM III

    Rochester, MN, Rochester, MN

  2. Complex Aortic Aneurysm Repair With Fenestrated Stent Grafts

    Rochester, MN

  3. Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial

    Jacksonville, FL, Rochester, MN

  4. A Study Evaluating the Safety and Effectiveness of the PulseRider® Aneurysm Neck Reconstruction Device Used in Conjunction With Endovascular Coil Embolization in the Treatment of Wide-Neck Bifurcation Intracranial Aneurysm

    Rochester, MN

  5. ENDOvascular Interventions With AngioMAX: The ENDOMAX Trial

    Rochester, MN

  6. Preventing Lymphedema in Axillary Lymph Node Dissection

    Jacksonville, FL, Rochester, MN

  7. A Study to Evaluate the Impact of Near-Infrared Vein Mapping on Outcomes and Satisfaction After Botox/Filler Treatment

    Scottsdale/Phoenix, AZ

  8. A Study to Explore the Renal Safety of Visipaque Injection 320 mgI/mL in Patients With Chronic Kidney Disease

    Rochester, MN

  9. A Study to Evaluate the Effectiveness and Safety of Rivaroxaban as Prophylaxis Treatment for Venous Thromboembolism (VTE) in Ambulatory Cancer Patients

    Rochester, MN

  10. A Study to Evaluate Whether or Not Selexipag is Effective and Safe in Patients with Chronic Thromboembolic Pulmonary Hypertension when the Disease is Inoperable or Persistent/Recurrent After Surgery

    Jacksonville, FL

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