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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 71-80 of 129 for transplant

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  • Study status: Open/Status Unknown
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  1. Fecal Microbiome Transplant National Registry

    Rochester, MN

  2. A Study to Develop a Database of Pancreas Transplant Recipients, to Form a Larger Cohort for Future Research

    Rochester, MN

  3. A Study to Analyze Tacrolimus Metabolism in Heart Transplant Patients

    Jacksonville, FL

  4. Pilot Study to Assess the Validity of "Liquid Biopsy" to Improve Diagnosis, Prognostic Assessment and Disease Monitoring in Patients Undergoing Liver Transplant for Hilar and Intrahepatic Cholangiocarcinoma

    Scottsdale/Phoenix, AZ

  5. Fecal Microbiota Transplant National Registry

    Rochester, MN

  6. A Study of Kidney Transplant Recipients: Development of a Database for a Multicenter Consortium

    Rochester, MN

  7. A Study to Evaluate Ultrasound Imaging in Renal Transplant Recipients

    Jacksonville, FL

  8. The Role of Genetics and Socioeconomic Factors in Outcomes After Kidney Transplantation in Hispanics and American Indians

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  9. APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO)

    Jacksonville, FL

  10. A Study to Compare Medical and Non-Medical Coping on Functional Outcomes and Caregiver Burden Among Liver Transplant Patients

    Jacksonville, FL

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