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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 811-820 of 2033 for surgery

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  1. Prevention Of Non-Surgical Bleeding By Management Of HeartMate II Patients Without Antiplatelet Therapy

    Rochester, MN

  2. E6201 Plus Dabrafenib For The Treatment Of Metastatic Melanoma Central Nervous System Metastases (CNS)

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  3. A Study Of The ExAblate UF V2 System For The Treatment Of Symptomatic Uterine Fibroids

    Rochester, MN

  4. A Phase 2 Study To Assess The Safety And Efficacy Of Intravitreal ONL1204 Ophthalmic Solution In Subjects With Mac-off Retinal Detachment

    Rochester, MN

  5. Clinical Evaluation of the CADence Device in Detection of Coronary Artery Diseases

    Rochester, MN

  6. A Study of the Possibility of the Use of Translumenal Endoscopic Omental Patch for Closure of Perforated Viscus

  7. Guiding Evidence Based Therapy Using Biomarker Intensified Treatment

    Rochester, MN

  8. Physiologic Effects of Sleep Restriction

    Rochester, MN

  9. Nitrate's Effect on Activity Tolerance in Heart Failure With Preserved Ejection Fraction

    Rochester, MN

  10. Inhaled Sodium Nitrite On Heart Failure With Preserved Ejection Fraction

    Rochester, MN

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