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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 811-820 of 2056 for surgery

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  1. Proton Therapy For Partial Breast Irradiation In Early Stage Breast Cancer

    Scottsdale/Phoenix, AZ

  2. Mild Hip Dysplasia

    Rochester, MN

  3. Colchicine and CRP in Atrial Fibrillation and AF Ablation

  4. A Randomized Study of Approaches in Total Hip Arthroplasty

    Rochester, MN

  5. A Pivotal Study Of The Premia Spine TOPS™ System

    Rochester, MN

  6. Prospective Study To Compare The Efficacy Of E.G.Scan To Detect Barrett's Esophagus Compared With Standard Endoscopy

    Rochester, MN

  7. A Study to Evaluate Autologous Adipose Derived Mesenchymal Stem Cells to Treat Spinal Cord Injury Patients

    Rochester, MN

  8. Ph1b/2 Dose-Escalation Study Of Entinostat With Pembrolizumab In NSCLC With Expansion Cohorts In NSCLC, Melanoma, And Colorectal Cancer

    Jacksonville, FL

  9. Stroke Mitigation in A-fib Reasoning Tool for Shared Decision Making

    Rochester, MN

  10. An Extension Study to QTI571A2301 to Evaluate the Long-Term Safety, Tolerability and Effectiveness of Imatinib in Severe Pulmonary Arterial Hypertension

    Rochester, MN

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