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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 621-630 of 2194 for surgery

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  1. The Affect of Low-Volume Bowel Preparation for Hospitalized Patients Colonoscopies

    Scottsdale/Phoenix, AZ

  2. Deuterated Phenanthrene Tetraol in Smokers Who Are at High Risk For Lung Cancer

    Rochester, MN

  3. A Study to Evaluate both the Efficacy and Safety Profile of CP-690,550 in Patients with Moderately to Severely Active Ulcerative Colitis

    Rochester, MN

  4. A Study to Assess Fluent Fluid Management System vs. Aquilex Fluid Control System in Women Undergoing Myomectomy and Polypectomy Procedures

    Jacksonville, FL

  5. A Study of Shoulder Motion and Impingement in Manual Wheelchair Users

    Rochester, MN

  6. PRESERVE-Zenith® Branch Endovascular Graft-Iliac Bifurcation Clinical Study

    Rochester, MN

  7. SI Joint Stabilization in Long Fusion to the Pelvis

    Rochester, MN

  8. A Study in Adult Subjects Undergoing Posterior Lumbar Spine Surgeries

    Rochester, MN

  9. A Dose-response of the Effects of Exendin-9,39 on GI Symptoms and Food Intake

    Rochester, MN

  10. Extending Preservation and Assessment Time of Donor Lungs Using the Toronto EVLP System™ at a Dedicated EVLP Facility

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