Kinematics After Total Knee Arthroplasty


About this study

The purpose of this study is to evaluate and compare implant kinematics of conventional mechanically aligned and anatomically aligned total knee arthroplasties (TKA) at 1 year post-operatively.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Males and females
  • Primary arthroplasty for treatment of osteoarthritis
  • Age between 40 and 80 years old
  • Willingness to provide written consent for study participation

Exclusion Criteria:

  • Revision arthroplasty
  • Pre-operative knee flexion lower than 90 degrees
  • Varus knee deformity greater than 15 degrees
  • Pre-operative valgus knee deformity
  • Presence of infections, highly communicable diseases or metastatic disease
  • Significant neurological or musculoskeletal disorders or disease that may interfere with normal gait or weight bearing
  • Congenital, developmental, or other bone disease or previous hip surgery that may, in the surgeon's judgment, interfere with total knee prosthesis survival or success
  • Presence of previous prosthetic knee or hip replacement device
  • BMI > 40
  • Pregnant women

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Kristin Zhao, Ph.D.

Closed for enrollment

More information


Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

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