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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 551-560 of 2056 for surgery

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  1. Comparison of Three Surgical Techniques to Achieve Patella Symmetry During Resection

    Rochester, MN

  2. The EMPrint™ Ablate And RESect Study In Patients With Metastatic Lung Tumors

    Rochester, MN

  3. Cardiovascular Outcomes Assessment Of The MitraClip Therapy Percutaneous Therapy For High Surgical Risk Patients

    Rochester, MN

  4. Micra Transcatheter Pacing Study

    Rochester, MN

  5. TX2® Low Profile TAA Endovascular Graft

    Rochester, MN

  6. Tailored Antiplatelet Therapy Following PCI

    La Crosse, WI, Eau Claire, WI, Scottsdale/Phoenix, AZ, Rochester, MN

  7. Testing An Active Form Of Tamoxifen (4-hydroxytamoxifen) Delivered Through The Breast Skin To Control Ductal Carcinoma In Situ (DCIS) Of The Breast

  8. A Study To Test The Combination Of Cabozantinib, Nivolumab, And Ipilimumab (CaboNivoIpi) For Advanced Differentiated Thyroid Cancer

    Jacksonville, FL, Rochester, MN

  9. A Study to Determine the Benefits of a Dedicated Athlete Training Program to Reduce the Effects of Aging

    Scottsdale/Phoenix, AZ

  10. A Study Using Spinal Stimulation During Exercise In Patients With Heart Failure

    Rochester, MN

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