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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 531-540 of 2195 for surgery

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  1. Cardiovascular Outcomes Assessment of the MitraClip Therapy Percutaneous Therapy for High Surgical Risk Patients

    Rochester, MN

  2. A Study of Speech Perception for Children with Cochlear Implants

    Rochester, MN

  3. Substrate Targeted Ablation Using the FlexAbility™ Ablation Catheter System for the Reduction of Ventricular Tachycardia

  4. A Study to Evaluate Hyperthermic Intraperitoneal Chemotherapy to Treat Patients with Pancreatic Cancer and Peritoneal Metastasis

    Rochester, MN

  5. Mesenteric Sparing for the Prevention of Recurrent Crohn's Disease

    Rochester, MN

  6. A Study of Perioperative Intravenous Lidocaine Infusion for Patients Undergoing Laparoscopic and Open Pancreatectomies

    Jacksonville, FL

  7. Characterization of Crohn’s Disease at a Cellular Level

    Rochester, MN

  8. A Study to Evaluate ADP-A2M4 with Pembrolizumab to Treat Recurrent or Metastatic Head and Neck Cancer

  9. Define in Humans With Compensated CHF and Renal Dysfunction, the Modulating Action of Chronic AT1 Receptor Blockade in Addition to ACE Inhibition on Cardiorenal and Humoral Function

    Rochester, MN

  10. Implementing Shared Decision Making (SDM) for Individualized CV Prevention (SDM4IP)

    Rochester, MN

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