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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 481-490 of 2195 for surgery

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  1. Kinematics After Total Knee Arthroplasty

    Rochester, MN

  2. Intra-Articular Dexamethasone to Prevent Post-Traumatic Osteoarthritis: A Pilot Study

    Rochester, MN

  3. A Study of Post-parotidectomy Facial Paresis Intraoperative and Postoperative Factors

    Scottsdale/Phoenix, AZ, Rochester, MN

  4. A Study to Evaluate Wearable Biofeedback Sleeve for Injury Prevention and Rehabilitation of Traumatic Knee Injury

    Minneapolis, MN, Rochester, MN

  5. A Study of the GORE® EXCLUDER® Conformable AAA Endoprosthesis in the Treatment of Abdominal Aortic Aneurysms

    Scottsdale/Phoenix, AZ

  6. Assessment of Coronary Plaque Composition

    Rochester, MN

  7. A Study to Evaluate the Safety of Intracoronary Infusion of Extracellular Vesicles in Patients with Acute Myocardial Infarction

    Rochester, MN

  8. ST Monitoring to Detect Acute Coronary Syndrome Events in Implantable Cardioverter Defibrillator Patients

    Rochester, MN

  9. A Study of the Effect of Dalcetrapib on Cardiovascular Risk for a Genetically Defined Population who have had a Recent Acute Coronary Syndrome Event

  10. Clinical Use of the Impella RP System

    Rochester, MN

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