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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 391-400 of 2028 for surgery

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  1. A Study To Evaluate A New Anti-Cancer Vaccine For Patients With Non-Small Cell Lung Cancer, Given After Tumor Removal By Surgery

    Rochester, MN

  2. A Study Of The Use Of Preoperative Antibiotics Given Preventively Prior To Kidney Stone Surgery To Patients At Moderate Risk Of Infection

    Scottsdale/Phoenix, AZ

  3. A Multi-center Study To Evaluate The Safety, Tolerability And Efficacy Of TIN816 In Patients At Risk For Acute Kidney Injury Following Cardiac Surgery

    Scottsdale/Phoenix, AZ

  4. Aspirin in Preventing Recurrence of Cancer in Patients With HER2 Negative Stage II-III Breast Cancer After Chemotherapy, Surgery, and/or Radiation Therapy

    La Crosse, WI, Albert Lea, MN, Eau Claire, WI, Mankato, MN, Rochester, MN

  5. A Study to Evaluate Gemcitabine, Cisplatin, and Nab-Paclitaxel to Treat Patients with High-Risk Liver Bile Duct Cancer Before Surgery

    Rochester, MN

  6. Radiation Therapy With Or Without Chemotherapy In Treating Patients With High-Risk Malignant Salivary Gland Tumors That Have Been Removed By Surgery

    Rochester, MN

  7. Comparison Of Acute Toxicities Between Patients Treated With Protons Or Intensity Modulated Radiation Therapy After Surgery For The Treatment Of Endometrial Or Cervical Cancer

    Albert Lea, MN, Scottsdale/Phoenix, AZ, Eau Claire, WI, Jacksonville, FL, La Crosse, WI, Mankato, MN, Rochester, MN

  8. TAS-102 And Radiation Therapy In Treating Patients With Rectal Cancer That Is Locally Recurrent, Metastatic, Or Cannot Be Removed By Surgery

    Scottsdale/Phoenix, AZ, Rochester, MN

  9. Cetuximab With Or Without Tivantinib In Treating Patients With Head And Neck Cancer That Is Recurrent, Metastatic, Or Cannot Be Removed By Surgery

    Scottsdale/Phoenix, AZ, Rochester, MN

  10. Atezolizumab With Or Without Cobimetinib In Treating Patients With Metastatic Bile Duct Cancer That Cannot Be Removed By Surgery Or Gallbladder Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

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