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Healthy Volunteer

What is this?
A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

What is this?
During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 381-390 of 2028 for surgery

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  1. A Study To Evaluate The Efficacy And Safety Of GDC-8264 In Preventing Cardiac Surgery-Associated Acute Kidney Injury (AKI) And Major Adverse Kidney Events (MAKE)

    Rochester, MN

  2. A Study to Evaluate Gemcitabine, Cisplatin, and Nab-Paclitaxel to Treat Patients with High-Risk Liver Bile Duct Cancer Before Surgery

    Rochester, MN

  3. Radiation Therapy With Or Without Chemotherapy In Treating Patients With High-Risk Malignant Salivary Gland Tumors That Have Been Removed By Surgery

    Rochester, MN

  4. Comparison Of Acute Toxicities Between Patients Treated With Protons Or Intensity Modulated Radiation Therapy After Surgery For The Treatment Of Endometrial Or Cervical Cancer

    Albert Lea, MN, Scottsdale/Phoenix, AZ, Eau Claire, WI, Jacksonville, FL, La Crosse, WI, Mankato, MN, Rochester, MN

  5. Alisertib And Fulvestrant In Treating Patients With Hormone Receptor Positive Breast Cancer That Is Metastatic Or Locally Advanced And Cannot Be Removed By Surgery

    Rochester, MN

  6. Transoral Surgery Followed By Low-Dose or Standard-Dose Radiation Therapy With or Without Chemotherapy in Treating Patients With HPV Positive Stage III-IVA Oropharyngeal Cancer

    Scottsdale/Phoenix, AZ

  7. Irinotecan And Cetuximab With Or Without Bevacizumab In Treating Patients With RAS Wild-Type Locally Advanced Or Metastatic Colorectal Cancer That Cannot Be Removed By Surgery

    Scottsdale/Phoenix, AZ

  8. Atezolizumab, Pemetrexed Disodium, Cisplatin, And Surgery With Or Without Radiation Therapy In Treating Patients With Stage I-III Pleural Malignant Mesothelioma

    Scottsdale/Phoenix, AZ, Rochester, MN

  9. Paclitaxel Albumin-Stabilized Nanoparticle Formulation And Bevacizumab Or Ipilimumab As First-Line Therapy In Treating Patients With Stage IV Melanoma That Cannot Be Removed By Surgery

    Scottsdale/Phoenix, AZ, Rochester, MN

  10. Radiation Therapy With Or Without Cisplatin In Treating Patients With Stage III-IV Squamous Cell Carcinoma Of The Head And Neck Who Have Undergone Surgery

    Rochester, MN

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