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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 2021-2030 of 2056 for surgery

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  1. Vascular Diseases Biorepository

    Rochester, MN

  2. A Study to Compare Outcomes from Deltoid Ligament Repair versus Not, for Patients who have Supination External Rotation Ankle Fractures

    Jacksonville, FL

  3. A Study to Determine the Feasibility of Doppler Ultrasound of Large Arterial Systems of the Brain as Vascular Involvement Markers in Presbyacusis and Presbyvestibulopathy

    Jacksonville, FL

  4. A Study to Integrate Clinical Characteristics, Family History and Novel Imaging Strategies for Evaluation of Right Ventricular Performance to Advance Treatment of Right Ventricular Dysfunction

    Rochester, MN

  5. Echocardiographic Measures of Pulmonary Vascular Distensibility and Effects on Lung Diffusing Capacity

    Rochester, MN, Rochester, MN

  6. COVID-19 (Coronavirus) Pandemic on Health and Healthcare

    Rochester, MN

  7. A Study to Evaluate Sex and Age Differences in Ehlers Danlos Syndrome Patients

    Jacksonville, FL

  8. A Study to Compare the Quality of Life of Patients Who Have Had Both an LVAD and then a Heart Transplant

    Rochester, MN

  9. Biomarkers in Aortic Stenosis - B.A.S.S.

    Rochester, MN, Jacksonville, FL

  10. Registry of Patients Prescribed Anticoagulation

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