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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1101-1110 of 2194 for surgery

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  1. Pemafibrate to Reduce Cardiovascular OutcoMes by Reducing Triglycerides IN patiENts With diabeTes (PROMINENT)

  2. A Study to Evaluate Intracoronary CD34+ Cell Administration in Patients With Early Coronary Atherosclerosis

    Rochester, MN

  3. Inhaled Beta-adrenergic Agonists to Treat Pulmonary Vascular Disease in Heart Failure With Preserved EF (BEAT HFpEF): A Randomized Controlled Trial

    Rochester, MN

  4. A Study to Evaluate Patiromer for the Management of Hyperkalemia in Subjects Receiving Renin-Angiotensin Aldosterone System Inhibitor (RAASi) Medications for the Treatment of Heart Failure (DIAMOND)

    Jacksonville, FL

  5. Preventing Lymphedema in Axillary Lymph Node Dissection

    Jacksonville, FL, Rochester, MN

  6. Cardiac Rehab for Advanced Heart Failure-LVAD Candidates

    Rochester, MN

  7. A Study to Evaluate Intramyocardial Injection of Autologous Umbilical Cord Blood Derived Mononuclear Cells During Surgical Repair of Hypoplastic Left Heart Syndrome

    Rochester, MN

  8. Dapagliflozin in Type 2 Diabetes or Pre-diabetes, and PRESERVED Ejection Fraction Heart Failure

    Rochester, MN

  9. A Study of Low Intensity Mechanoreflex during Exercise in Healthy Adults

    Rochester, MN

  10. A Study to See if Clinical Cardiac MRI Scanning Can Cause DNA Damage

    Rochester, MN

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