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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 21-30 of 76 for soft tissue sarcoma

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  1. A Two-part Phase IIb Trial of Vigil in Ewing's Sarcoma

    Jacksonville, FL

  2. A Study to Compare Early Use of Vinorelbine and Maintenance Therapy for Patients With High Risk Rhabdomyosarcoma

    Rochester, MN

  3. Treatment of Milademetan Versus Trabectedin in Patient With Dedifferentiated Liposarcoma (MANTRA)

    Jacksonville, FL

  4. Pazopanib as Front-Line Therapy in Patients With Non-Resectable or Metastatic Soft Tissue Sarcomas Who Are Not Candidates for Chemotherapy

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  5. Envafolimab And Envafolimab With Ipilimumab In Patients With Undifferentiated Pleomorphic Sarcoma Or Myxofibrosarcoma

    Jacksonville, FL, Rochester, MN

  6. A Study to Test the Addition of Nivolumab to Chemotherapy to Treat Soft Tissue Sarcoma

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  7. A Phase II, Multicenter Study of the EZH2 Inhibitor Tazemetostat in Adult Subjects With INI1-Negative Tumors or Relapsed/Refractory Synovial Sarcoma

    Jacksonville, FL

  8. A Study to Evaluate Trabectedin with Olaparib in Advanced Unresectable or Metastatic Sarcoma

    Rochester, MN

  9. A Randomized Phase 3 Trial of TRC105 and Pazopanib Versus Pazopanib Alone in Patients with Advanced Angiosarcoma (TAPPAS)

    Jacksonville, FL, Rochester, MN

  10. A Trial of TTI-621 in Combination With Doxorubicin in Patients With Leiomyosarcoma

    Jacksonville, FL

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