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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 11-20 of 141 for pancreatic cancer

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  1. A Study of Rucaparib in Patients With Pancreatic Cancer and a Known Deleterious BRCA Mutation

    Rochester, MN

  2. High-Dose Radiation Therapy Versus Standard Care in Treating Patients With Pancreatic Cancer That Cannot Be Removed By Surgery

    Rochester, MN, La Crosse, WI

  3. BPM31510 Administered Intravenously With or Without Gemcitabine in Advanced Pancreatic Cancer Patients

    Scottsdale/Phoenix, AZ

  4. A Study to Test Adding Pembrolizumab to Olaparib Alone as Therapy for Patients with Pancreatic Cancer That Has Spread with Inherited BRCA Mutations

    Eau Claire, WI, La Crosse, WI, Rochester, MN

  5. Safety and Efficacy of Combination Listeria/GVAX Pancreas Vaccine in the Pancreatic Cancer Setting

    Rochester, MN

  6. Gemcitabine Hydrochloride in Treating Patients with Locally Advanced Pancreatic Cancer

    Rochester, MN

  7. Dignity Therapy/Life Plan in Patients With Pancreatic or Advanced Lung Cancer

    Rochester, MN

  8. Phase 2b Study of GC4711 in Combination With SBRT for Nonmetastatic Pancreatic Cancer

    Rochester, MN

  9. A Study of Pancreatic Polypeptide Response in Patients with Diabetes Mellitus with and without Pancreatic Cancer

    Rochester, MN

  10. Nab-paclitaxel and Gemcitabine vs Gemcitabine Alone as Adjuvant Therapy for Patients with Resected Pancreatic Cancer (the "Apact" Study)

    Scottsdale/Phoenix, AZ, Rochester, MN

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