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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 136 for pancreatic cancer

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  1. A Randomized Study of Olaparib or Placebo in Patients With Surgically Removed Pancreatic Cancer Who Have a BRCA1, BRCA2 or PALB2 Mutation, The APOLLO Trial

    Rochester, MN

  2. PERT for Treatment of Exocrine Pancreatic Insufficiency in Patients With Unresectable Pancreatic Cancer

    Jacksonville, FL

  3. Phase II Randomized Trial of mFOLFIRINOX +/- Ramucirumab in Advanced Pancreatic Cancer

    Scottsdale/Phoenix, AZ

  4. A Study to Analyze the Safety and Effectiveness of the NanoKnife® System in Unresectable Stage 3 Pancreatic Adenocarcinom Patients

    Rochester, MN, Jacksonville, FL

  5. Study of SBP-101 in Pancreatic Cancer

    Scottsdale/Phoenix, AZ

  6. Endoscopic Ultrasound-guided Ethanol Injection of Pancreatic Cystic Neoplasms

    Rochester, MN

  7. Phase II Study of NGC-Triple Regimen in Potentially Resectable Pancreatic Cancer Patients

    Scottsdale/Phoenix, AZ, Rochester, MN

  8. A Study of Rucaparib in Patients With Pancreatic Cancer and a Known Deleterious BRCA Mutation

    Rochester, MN

  9. BPM31510 Administered Intravenously With or Without Gemcitabine in Advanced Pancreatic Cancer Patients

    Scottsdale/Phoenix, AZ

  10. Phase 2 Nab®-Paclitaxel (Abraxane®) Plus Gemcitabine in Subjects with Locally Advanced Pancreatic Cancer (LAPC)

    Scottsdale/Phoenix, AZ

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