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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 31-40 of 118 for neuro

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  1. A Study Using Targeted Inhibitors to Treat Specific Tumor Mutations in Patients with Meningiomas

    Jacksonville, FL, Rochester, MN

  2. A Study of 9-ING-41 in Patients with Advanced Cancers

    Rochester, MN, Scottsdale/Phoenix, AZ

  3. A Study to Evaluate the Use of AR-42 (Histone Deacetylase Inhibitor) in the Treatment of Vestibular Schwannoma and Meningioma

    Rochester, MN

  4. Maintenance Chemotherapy or Observation Following Induction Chemotherapy and Radiation Therapy in Treating Younger Patients with Newly Diagnosed Ependymoma

    Rochester, MN

  5. Modafinil in Treating Children with Memory and Attention Problems Caused by Cancer Treatment for a Brain Tumor

    Rochester, MN

  6. A Study to Use a Patient Monitoring Application that Monitors Physiological Data, Psychosocial Data, and Responses to Survey Questions in Patients Undergoing Cranial or Spinal Surgery

    Rochester, MN

  7. Vorinostat, Temozolomide, or Bevacizumab in Combination with Radiation Therapy Followed by Bevacizumab and Temozolomide in Young Patients with Newly Diagnosed High-Grade Glioma

    Rochester, MN

  8. Viral Therapy in Treating Patients with Recurrent Glioblastoma Multiforme

    Rochester, MN

  9. A Study to Evaluate CB-839 With Radiation Therapy and Temozolomide in Treating Participants With IDH-Mutated Diffuse Astrocytoma or Anaplastic Astrocytoma

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  10. Study of Pomalidomide for Treatment of Relapsed/Refractory Primary Central Nervous System Lymphoma and Newly Diagnosed or Relapsed/Refractory Intraocular Lymphoma

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

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