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Healthy Volunteer

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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 135 for neuro

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  1. NEURO-TTRansform: A Study to Evaluate the Efficacy and Safety of AKCEA-TTR-LRx in Participants With Hereditary Transthyretin-Mediated Amyloid Polyneuropathy

    Rochester, MN, Jacksonville, FL

  2. Pazopanib Hydrochloride in Treating Patients with Advanced or Progressive Malignant Pheochromocytoma or Paraganglioma

    Jacksonville, FL, Rochester, MN

  3. A Study to Compare Single Fraction Stereotactic Radiosurgery Compared with Fractionated Stereotactic Radiosurgery in Treating Patients With Resected Metastatic Brain Disease

    Jacksonville, FL, Rochester, MN, Scottsdale/Phoenix, AZ

  4. Armodafinil in Reducing Cancer-Related Fatigue in Patients With High Grade Glioma

    Scottsdale/Phoenix, AZ, Rochester, MN

  5. A Study of 9-ING-41 in Patients with Advanced Cancers

    Rochester, MN

  6. 18F-DOPA-PET in Planning Surgery in Patients With Gliomas

    Rochester, MN, Scottsdale/Phoenix, AZ

  7. A Study of Fluorine F 18 Fluorodopa-Labeled PET Scans for Planning Surgery and Radiation Therapy to Treat Patients who have Newly Diagnosed High- or Low-Grade Glioma Brain Cancer Tumors

    Rochester, MN

  8. A Clinical and Molecular Risk-Directed Therapy for Newly Diagnosed Medulloblastoma

  9. A Study to Evaluate Genetic Testing in Guiding Treatment for Patients with Brain Metastases

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  10. Study of Treating Patients with Vestibular Schwannoma with Aspirin

    Rochester, MN

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