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Healthy Volunteer

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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 11-20 of 118 for neuro

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  1. A Study to Evaluate Genetic Testing in Guiding Treatment for Patients with Brain Metastases

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  2. Vaccine Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

    Rochester, MN

  3. A Study Testing the Effect of Immunotherapy (Ipilimumab and Nivolumab) in Patients with Recurrent Glioblastoma with Elevated Mutational Burden

    Scottsdale/Phoenix, AZ, Rochester, MN, Eau Claire, WI, Jacksonville, FL, La Crosse, WI

  4. Armodafinil in Reducing Cancer-Related Fatigue in Patients With High Grade Glioma

    Scottsdale/Phoenix, AZ, Rochester, MN

  5. Combination Chemotherapy in Treating Younger Patients with Newly Diagnosed, Non-Metastatic Desmoplastic Medulloblastoma

    Rochester, MN

  6. A Study to Evaluate Pembrolizumab with Standard Therapy to Treat Newly-diagnosed Glioblastoma

    Rochester, MN, Scottsdale/Phoenix, AZ

  7. Bevacizumab with or without Anti-Endoglin Monoclonal Antibody TRC105 in Treating Patients with Recurrent Glioblastoma Multiforme

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  8. Rovalpituzumab Tesirine in Delta-Like Protein 3-Expressing Advanced Solid Tumors

    Scottsdale/Phoenix, AZ, Rochester, MN

  9. Temozolomide With or Without Veliparib in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

    Jacksonville, FL, Rochester, MN, Scottsdale/Phoenix, AZ

  10. A Study to Assess the Safety and Tolerability of ADI-PEG 20 Combined with Pemetrexed and Cisplatinin in Subjects with Tumors Requiring Arginine

    Rochester, MN

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