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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 51-60 of 187 for lung disease

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  1. A Study of the Safety and Effectiveness of HBI-8000 with Nivolumab to Treat Melanoma, Renal Cell Carcinoma and Non-Small Cell Lung Cancer

  2. A Study To Evaluate the Effect of Canakinumab or Pembrolizumab Given as Monotherapy or in Combination as Neo-adjuvant Treatment for Subjects With Early Stages NSCLC

  3. Myositis Interstitial Lung Disease Nintedanib Trial

    Scottsdale/Phoenix, AZ

  4. A Study to Evaluate Wellness Coaching for Caregivers of Thoracic Transplant Candidates

    Rochester, MN

  5. A Study of a Multicomponent Intervention Aimed at Decreasing Perception of Dyspnea in Participants with Lung Disease Who are Obese

    Rochester, MN

  6. A Global Study to Assess the Effects of Durvalumab + Domvanalimab Following Concurrent Chemoradiation in Participants With Stage III Unresectable NSCLC

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  7. Pembrolizumab With or Without Anetumab Ravtansine in Treating Patients With Mesothelin-Positive Pleural Mesothelioma

    Jacksonville, FL, Rochester, MN

  8. Atezolizumab Immunotherapy in Patients With Advanced NSCLC (AJCC 7th Edition)

  9. Home-based Health Management of Chronic Obstructive Lung Disease (COPD) Patients

    Rochester, MN

  10. Evaluation of CRS-207 With Pembrolizumab in Previously Treated MPM

    Rochester, MN

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