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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 1027 for hematology

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  1. A Study of PROQOL (Patient Reported Outcome Quality of Life) Tool in the Hematology and Oncology Population

    Rochester, MN

  2. A Study to Evaluate Reiki Therapy as an Intervention in Hematology/Oncology Cancer Patients Hospitalized in an Inpatient Setting

    Rochester, MN

  3. Oral Ketamine in the Treatment of Depression and Anxiety in Patients with Cancer

    Scottsdale/Phoenix, AZ

  4. Efficacy and Safety of IV Rigosertib in MDS Patients With Excess Blasts Progressing After Azacitidine or Decitabine

    Rochester, MN

  5. Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-158/KEYNOTE-158)

    Rochester, MN

  6. A Study to Evaluate the Safety and Effectiveness of CAEL-101 and Plasma Cell Dyscrasia Treatment vs. Placebo and Plasma Cell Dyscrasia Tretment to Treat Patients with Mayo Stage IIIb AL Amyloidosis

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  7. A Study of Oral LGH447 in Patients with Relapsed and/or Refractory Multiple Myeloma

    Rochester, MN

  8. Oral Rigosertib in Low Risk MDS Patients Refractory to ESAs

    Rochester, MN

  9. A Study to Determine the Effectiveness and Safety of a New Nicotine Replacement Therapy

    Scottsdale/Phoenix, AZ

  10. BT062 in Combination With Lenalidomide or Pomalidomide and Dexamethasone in Patients With Multiple Myeloma

    Jacksonville, FL

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