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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 51-60 of 81 for hematology

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  1. A Registry for the Collection of Biological and Clinical Data for Studies of Immune System Related Blood Disorders

    Rochester, MN

  2. Evaluating Intestinal Microbiome and Immune Function in Lymphoma

    Rochester, MN

  3. A Study to Evaluate Minimal Residual Disease in Chronic Lymphocytic Leukemia

    Rochester, MN

  4. A Study of Hematopoiesis in Patients with Monoclonal B Cell Lymphocytosis (MBL), B-Chronic Lymphocytic Leukemia (CLL), and Healthy Controls

    Rochester, MN

  5. Methylation and Chromatin Abnormalities in Myelodysplastic Syndromes and Chronic Myelomonocytic leukemia.

    Rochester, MN

  6. Benevolent Tumor Tissue Repository Fighting for the Legacy of our Young

    Rochester, MN

  7. Exploring Mechanisms of Action and Resistance of Therapeutic Agents in Patients with B-cell Malignancies

    Jacksonville, FL

  8. Biorepository for Acute Leukemia Research

    Rochester, MN

  9. Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies

    Rochester, MN

  10. A Study of the Health Issues of Bleeding Disorders

    Rochester, MN

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