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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 41-50 of 982 for hematology

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  1. Stereotactic Radiation Therapy for Pediatric Sarcomas

    Rochester, MN

  2. Phase Ib Study of Select Drug Combinations in Patients With Lower Risk MDS

    Rochester, MN

  3. A Study of Caplacizumab in Patients with Acquired Thrombotic Thrombocytopenic Purpura

    Rochester, MN

  4. Evaluation of Safety and Efficacy of Allo GDA-201 NK Cells in Patients With Relapsed/Refractory B Cell NHL

    Jacksonville, FL

  5. A Study to Evaluate the Effectiveness and Safety of PANZYGA in Pediatric Patients with Chronic Immune Thrombocytopenia (ITP)

    Rochester, MN

  6. A Study of WVT078 in Patients With Multiple Myeloma

    Rochester, MN

  7. Randomized Study of Individualized Care Plans for Hematopoietic Cell Transplant Survivors

    Scottsdale/Phoenix, AZ, Rochester, MN

  8. A Study of the Impact of the Amount of Time Between the Collection of Whole Blood and the Isolation of the White Blood Cells

  9. A Study of Oral LOXO-305 in Patients With Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma or Non-Hodgkin Lymphoma

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  10. Early Detection of Hemodynamic Decompensation in Humans

    Rochester, MN

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