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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 41-50 of 981 for hematology

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  1. Stereotactic Radiation Therapy for Pediatric Sarcomas

    Rochester, MN

  2. Phase Ib Study of Select Drug Combinations in Patients With Lower Risk MDS

    Rochester, MN

  3. Evaluation of Safety and Efficacy of Allo GDA-201 NK Cells in Patients With Relapsed/Refractory B Cell NHL

    Jacksonville, FL

  4. A Study of Caplacizumab in Patients with Acquired Thrombotic Thrombocytopenic Purpura

    Rochester, MN

  5. A Study to Evaluate the Effectiveness and Safety of PANZYGA in Pediatric Patients with Chronic Immune Thrombocytopenia (ITP)

    Rochester, MN

  6. Phase 2 Study of Inhaled Lipid Cisplatin in Pulmonary Recurrent Osteosarcoma

  7. Ph 1b Study to Evaluate GSK2110183 in Combination with Bortezomib and Dexamethasone in Subjects with Multiple Myeloma

    Scottsdale/Phoenix, AZ

  8. Brentuximab Vedotin in Patients With CD30-positive Nonlymphomatous Malignancies

    Jacksonville, FL

  9. A Study of the Safety and Effectiveness of NEOD001 for Treating Previously Treated Patients with Persistent Cardiac Dysfunction Related to Light Chain Amyloidosis

    Jacksonville, FL, Rochester, MN

  10. Isatuximab in Treating Patients With Relapsed or Refractory Primary Amyloidosis

    Rochester, MN

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