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Healthy Volunteer

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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 281-290 of 304 for heart disease

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  1. Spontaneous Coronary Artery Dissection: Case Review

    Rochester, MN

  2. Systolic Pressure Intervention Trial Factors Affecting Atherosclerosis Study

    Jacksonville, FL

  3. A Study to Identify Risk Factors for Progression from Acute Pericarditis to Constrictive Pericardial Disease

    Rochester, MN

  4. A Study to Evaluate Left and Right Ventricular Function in Relation to Exercise Capacity in Breast Cancer Survivors

    Jacksonville, FL

  5. A Study to Evaluate Cardiotoxicity in Total Hip and Knee Arthroplasty

    Rochester, MN

  6. Artificial Intelligence-enabled Electrocardiogram and Phonocardiogram to improve detection of Congenital Heart Disease

    Rochester, MN

  7. Understanding the Contents of Exhaled Breath in Health and Disease

    Rochester, MN

  8. In Situ Measurement of Anti-Apoptotic Phenotype in the Pulmonary Arterial Endothelium and Its Association with Pre-Capillary Disease in Pulmonary Hypertension

    Rochester, MN

  9. A Study to Evaluate Pregnancy in Adults with Congenital Heart Disease

    Rochester, MN

  10. Fetal Cardiac MR Images to Improve the Diagnostic Accuracy of Prenatal Imaging for Congenital Heart Disease

    Rochester, MN

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