A Study to Evaluate the Severity of Valvular Lesions by Using a New Investigational Imaging Protocol


About this study

The purpose of this study is to evaluate the severity of valvular lesions by using a new investigational imaging protocol. This new protocol includes 3D volumetric evaluation and is designed to see if such measurements are useful to be added to regular echo studies. An investigational image protocol means that the protocol is still experimental and isn’t approved by the U.S. Food and Drug Administration (FDA).

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Patients 18 years and older who are referred to the valvular disease pod of the echocardiography laboratory will be recruited.

Exclusion Criteria: 

  • Subjects with poor apical images.
  • Patients with congenital heart anomalies.
  • Patients with multi-valvular disease.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Sorin Pislaru, M.D., Ph.D.

Closed for enrollment

Contact information:

Sorin Pislaru M.D., Ph.D.

(507) 266-3626


More information


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