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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 111-120 of 143 for colorectal

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  1. Endoscopic Resection of Large Colorectal Polyps

    Jacksonville, FL

  2. Blood and Stool Sample Collection in Subjects Participating in Colorectal Cancer Screening

    Rochester, MN

  3. A Study to Assess a New Personalized Tool for Colorectal Cancer Peritoneal Disease Treatment

    Rochester, MN

  4. A Study of SC-006 in Subjects With Advanced Cancer

  5. Collecting Blood and Stool Samples to Detect Colorectal Cancer or Advanced Neoplasia in Lynch Syndrome Patients, CORAL Study

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  6. A Comprehensive Translational Research Platform for Colorectal Cancer

    Rochester, MN

  7. Colorectal Resection in Emergency General Surgery

  8. Patients with Inflammatory Bowel Disease (IBD) are at Increased Risk for Colorectal Cancer and Early Dysplasia

    Rochester, MN

  9. RP2/RP3 in Combination With Atezolizumab and Bevacizumab for the Treatment of Patients With CRC

    Scottsdale/Phoenix, AZ, Rochester, MN

  10. A Study of Participant Preferences for Education and Decision Making in K-ras Tumor Molecular Testing for Colorectal Cancer

    Rochester, MN

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