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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 101-110 of 126 for colorectal

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  1. A Study of the Quality of Life of Patients who have Hereditary Nonpolyposis Colorectal Cancer

    Rochester, MN

  2. Endoscopic Resection of Large Colorectal Polyps

    Jacksonville, FL

  3. A Study of SC-006 in Subjects With Advanced Cancer

  4. A Comprehensive Translational Research Platform for Colorectal Cancer

    Rochester, MN

  5. Colorectal Resection in Emergency General Surgery

  6. Patients with Inflammatory Bowel Disease (IBD) are at Increased Risk for Colorectal Cancer and Early Dysplasia

    Rochester, MN

  7. RP2/RP3 in Combination With Atezolizumab and Bevacizumab for the Treatment of Patients With CRC

    Scottsdale/Phoenix, AZ, Rochester, MN

  8. Time Longitudinal Study of the Microbiome in Colorectal Cancer Subjects

    Rochester, MN

  9. A Study of Participant Preferences for Education and Decision Making in K-ras Tumor Molecular Testing for Colorectal Cancer

    Rochester, MN

  10. Detection of Recurrent Colorectal Cancer by Assay of Novel Methylated DNA Markers in Plasma

    Rochester, MN, Jacksonville, FL

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