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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 10 for cartilage repair

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  1. Trial of REcycled CartiLage Auto/Allo IMplantation for the Treatment and Repair of Focal Knee Cartilage Defects (RECLAIM)

    Rochester, MN

  2. Arthroscopic Partial Meniscectomy in OA: A 12-Year Follow-Up

    Rochester, MN

  3. Confirmatory Study of NeoCart in Knee Cartilage Repair

    Rochester, MN

  4. Study Comparing NOVOCART 3D and Microfracture Surgery for Treatment of Articular Knee Cartilage

    Rochester, MN

  5. Agili-C™ Implant Performance Evaluation

    Rochester, MN

  6. Outcomes of Meniscus Root Repair Using a Transtibial Pullout Technique

    Rochester, MN

  7. Pain Control for Undergoing Costal Cartilage Harvesting

    Rochester, MN

  8. Study of Suture Repair of Torn Meniscus in the Knee

    Rochester, MN

  9. REcycled CartiLage Auto/Allo IMplantation

    Rochester, MN

  10. Metrics of Osteochondral Allografts (MOCA) Registry of the Knee

    Rochester, MN

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