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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 21-30 of 796 for cardiovascular

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  1. Application for Self-Monitoring of Cardiovascular Risk

    Rochester, MN

  2. Acute Effects of Inorganic Nitrite on Cardiovascular Hemodynamics in Heart Failure With Preserved Ejection Fraction

    Rochester, MN

  3. Cardiovascular Outcomes Assessment of the MitraClip Therapy Percutaneous Therapy for High Surgical Risk Patients

    Rochester, MN

  4. Inclisiran for Participants With Atherosclerotic Cardiovascular Disease and Elevated Low-density Lipoprotein Cholesterol

    Rochester, MN

  5. The Influence of Pedal Rate on Activation of Locomotor Afferents and Cardiovascular Responses

    Rochester, MN

  6. Cardiovascular Effects of Adderall in Healthy Young Adults

    Rochester, MN

  7. Pemafibrate to Reduce Cardiovascular OutcoMes by Reducing Triglycerides IN patiENts With diabeTes (PROMINENT)

    La Crosse, WI

  8. Further Cardiovascular Outcomes Research with PCSK9 Inhibition in Subjects With Elevated Risk

    Scottsdale/Phoenix, AZ

  9. A Study to Evaluate Cardiovascular Effects of High Intensity Interval Training in Individuals with Paraplegia

    Rochester, MN

  10. The Combined Influence of Pedal Rate and Venous Distension on Exercise Activation of Locomotor Afferents and Cardiovascular Responses

    Rochester, MN

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