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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 11-20 of 796 for cardiovascular

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  1. Atrial Fibrillation Screening and Education Study

    Rochester, MN

  2. Get Going: Accelerometer-Based Intervention to Promote Physical Activity in Frail Older Adults

    La Crosse, WI, Rochester, MN

  3. A Study of Stress Management Intervention in a Women's Heart Clinic, The Heart SMART Program

    Rochester, MN

  4. Olive Oil and Cardiovascular Health

    Rochester, MN

  5. Cardiovascular Effects of Energy Drinks in Healthy Adults

    Rochester, MN

  6. A Study to Compare the Effectiveness of Invasive versus Conservative Medical Approaches in Patients with Stable Ischemic Heart Disease and Advanced Chronic Kidney Disease

    Scottsdale/Phoenix, AZ

  7. Preventing Anthracycline Cardiovascular Toxicity with Statins (PREVENT)

    Rochester, MN

  8. Treating Breast Cancer Patients Undergoing Trastuzumab Treatment with Carvedilol to Reduce Incidence of Heart Failure

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  9. Evaluation of Major Cardiovascular Events in Patients With, or at High Risk for, Cardiovascular Disease Who Are Statin Intolerant Treated With Bempedoic Acid (ETC-1002) or Placebo

    La Crosse, WI

  10. Molecular Analysis of Blood for the Detection of Cardiovascular Pathogens

    Rochester, MN

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