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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 501-510 of 847 for cardiovascular

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  1. Machine Learning Guided Precision Genetic Testing for Identification of Monogenic Cardiovascular Disorders

    Rochester, MN

  2. Burden of Cardiovascular Disease in Master Athletes With a Lifetime History of High-Intensity Endurance

    Rochester, MN

  3. VALUE Trial

    Rochester, MN

  4. Obese Adults with Cardiovascular Disease Evaluated in a Novel Cardiometabolic Clinic

    Rochester, MN

  5. HTN Management and Cardiovascular Adverse Event Prevention in B-Cell Malignancies Undergoing BTKi

    Rochester, MN

  6. Hypothalamic Amenorrhea as a Fertility Status Marker for Cardiovascular Health (ARCH)

    Jacksonville, FL

  7. A Study to Evaluate a New Method of Quantifying Muscle O2 Uptake and Blood Flow Using Near-Infrared Spectroscopy

    Rochester, MN

  8. Body Composition and Fluid Status Using Non-Invasive Impedance

    Rochester, MN

  9. A Study to Evaluate Two Dimensional vs. Three Dimensional Carotid Artery Plaque Burden with Cardiovascular Risk

    Scottsdale/Phoenix, AZ

  10. Assessment of Body Volume (total and regional) in Association with Metabolic Risk Factors for Heart Disease

    Rochester, MN

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