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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 61-70 of 691 for cancer

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  1. CJNJ-67652000 and Prednisone for the Treatment of Men With Metastatic Castration-Resistant Prostate Cancer and SPOP Gene Mutations

    Jacksonville, FL, Rochester, MN, Scottsdale/Phoenix, AZ

  2. Neoadjuvant dual checkpoint blockade with PD1 and LAG-3 inhibition in resectable Non-small cell lung Cancer

    Rochester, MN

  3. Synergy with Grid Therapy and Immune Checkpoint Inhibitors in Stage IV Non-Small Cell Lung Cancer

    Rochester, MN

  4. A Study to Evaluate Oncologic Outcomes and Quality of Life in Sinonasal Cancer Patients

    Rochester, MN

  5. Monitoring Neoadjuvant Chemotherapy of Breast Cancer Using 3D Subharmonic Aided Pressure Estimation

    Rochester, MN

  6. Pre-Op / Post-Op Hypofractionation Radiotherapy in Breast Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL

  7. Ulixertinib in People With Histiocytic Neoplasms

    Rochester, MN

  8. A Study to Evaluate Enfortumab Vedotin to Treat Metastatic Squamous Cell Carcinoma of the Penis

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  9. Single arm pilot trial of adaptive therapy (AT) with capecitabine for the treatment of breast cancer

    Scottsdale/Phoenix, AZ

  10. Vilastobart (XTX101) Monotherapy and Vilastobart and Atezolizumab Combination Therapy in Advanced Solid Tumors

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

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