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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 333 for breast cancer

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  1. Engineering Gut Microbiome to Target Breast Cancer

    Jacksonville, FL

  2. Anastrozole and Letrozole After Surgery for the Treatment of Stage I-III Breast Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  3. Taselisib and Enzalutamide in Treating Patients With Androgen Receptor Positive Triple-Negative Metastatic Breast Cancer

    Rochester, MN

  4. A Study to Continue A Long Term Follow-Up of Patients Given Doxorubicin-Cyclophosphamide Therapy for Breast Cancer

    La Crosse, WI

  5. Letrozole After Tamoxifen in Treating Women With Breast Cancer

    La Crosse, WI

  6. Breast-Conserving Surgery and Radiation Therapy in Patients with Multiple Ipsilateral Breast Cancer

    Rochester, MN

  7. S1207 Hormone Therapy With or Without Everolimus in Treating Patients With Breast Cancer

    Rochester, MN

  8. Exercise Preconditioning and Breast Cancer Cardiotoxicity

    Scottsdale/Phoenix, AZ

  9. Comparison of Combination Chemotherapy Regimens in Treating Older Women Who Have Undergone Surgery for Breast Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  10. Eliminating Breast Cancer Surgery in Exceptional Responders with Neoadjuvant Systemic Therapy

    Rochester, MN

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