Overview

About this study

The purpose of this study is to examine the capability of contrast enhanced breast PCD-CT in staging breast cancer within the breasts and regional nodes of human subjects. Developing and using a PCD-CT imaging technique and postprocessing algorithms, dedicated for breast cancer detection.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Adult female patients 18 to 99 years of age.
  • Patients with proven breast cancer and nodal metastases referred for staging breast MR within the Department of Radiology.
  • Patients who are able and willing to sign the informed consent.
  • Negative pregnancy test if subject is of child-bearing age (females of child-bearing potential will be screened for pregnancy using a urine pregnancy test, which will be administered by the unit study coordinator at no cost to the patient).

Exclusion Criteria:

  • Minors under 18 years of age.
  • Patients unable to provide written informed consent.
  • Pregnancy.
  • eGFR ≤ 30 (4,5).
  • History of prior moderate or severe contrast reaction including unresponsiveness, severe respiratory distress, convulsions, arrhythmia, cardiopulmonary distress, progressive angioedema, laryngeal edema, dyspnea, bronchospasm, symptomatic tachycardia, symptomatic bradycardia, hypotension, hypertensive crisis.
  • Any history of premedication prior to iodinated contrast.
  • Patients that consent to participation but do not undergo their clinically indicated MR scanning for any reason (e.g., bad IV, infiltration, reaction, change in indication).

Eligibility last updated 8/24/21. Questions regarding updates should be directed to the study team contact.

 

 

More information

Publications

Publications are currently not available
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CLS-20533404

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